Research Keywords 【 display / non-display

  • Digestive enzymes, Human pancreatic lipase, E. coli expression system, carbohydrate-binding acitivity

Research Pursuits 【 display / non-display

  • Investigation of the carbohydarate-binding activity of various digestive enzymes and proteases.
    Biological significances of the new lectins from Pleurocybella porrigens.

Educational Pursuits 【 display / non-display

  • Biochemistry field, especially focusing on the carbohydrates, and glycobiology. Biological recognition events including the carbohydrate recognition and protein-carbohydrate interactions, and natural immunology.

Future Research Plans, Research Prospects, and Joint Research Potential 【 display / non-display

  • An active recombinant human pancreatic lipase (recHPL) was successfully prepared for the first time from the Escherichia coli expression system using short strep-tag II (ST II). The recHPL-ST II was purified on a Strep-Tactin-Sepharose column. After refolding by stepwise dialyses followed by gel filtration, 1.8-6 mg of active recHPL-ST II was obtained from 1 L of culture. The recHPL showed the equal specific activity and the same pH-dependency and stability compared to those of native porcine pancreatic lipase at 37 °C.

Degree 【 display / non-display

  • Bachelor of Science, 1978/03

  • Master of Science, 1980/03

  • Docter of Science, 1985/12

Campus Career 【 display / non-display

  • Trustee and Vice President, Trustee and Vice President

  • Graduate School of Humanities and Sciences, Research Organization, the Core Section The Natural/Applied Sciences Division, Professor

  • Graduate School of Humanities and Sciences, Research Organization, the Core Section The Natural/Applied Sciences Division, Professor

  • Graduate School of Humanities and Sciences, Education Organization, Master's Program Advanced Sciences

  • Graduate School of Humanities and Sciences, Education Organization, Master's Program Advanced Sciences

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External Career 【 display / non-display

  • Tokyo University Faculty of Science , part-time lecturer, 2012.04 - 2014.09

  • , 2017.03 - 2019.02

Research Field 【 display / non-display

 

Books 【 display / non-display

  • Experimental Glycobiology

    Development of neoglycoconjugate probes and detection of lectins, Elsevier Science Publishers, 2008.08, Haruko Ogawa and Keiko Nakagawa, Taniguchi Naoyuki, Textbook

  • 未来を拓く糖鎖科学

    Development of neo-glycoconjugate probes useful for lectin screening and interaction analyses, Kinpodo, 2005.12, Haruko Ogawa, Keiko Satou, 永井克孝、川崎敏祐 他9名, Book, 81-82

  • タンパク質科学イラストレイテッド

    3章8「糖鎖修飾」, 羊土社, 2005.11, 佐野琴音、 小川温子, 竹縄忠臣編, Textbook, 168-179

  • 「バイオデータベース利用法-検索からバイオインフォマティクスまで」

    学進出版2005.03, 金久實、小川温子、西原祥子, Textbook

  • 「血小板生物学」

    「フィブロネクチン、ビトロネクチン」, メディカルレビュー社 , 2004.06, 小川温子、岩城はるひ  , 池田康夫・丸山征郎, Book, 359-365

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Papers 【 display / non-display

  • Glycosylation and ligand-binding activities of rat plasma fibronectin during liver regeneration after partial hepatectomy

    Carbohydrate Research, 2008.03, Kotone Sano, Miho Asahi, Maiko Yanagibashi, Noritaka Hashii, Satsuki Itoh, Nana Kawasaki, Haruko Ogawa, Original, Research paper (scientific journal), Capital Author

  • Binding activity of vitronectin to collagen and fibrinolytic factors

    Science of the living body, 2008.03, 佐野琴音 小川温子, Original, Research paper (scientific journal), Capital Author

  • Changes in glycosylation of vitronectin modulates multimerization and collagen binding during liver regeneration.

    Glycobiology, 2007.07, Sano,K.,Asanuma-Date,K.,Arisaka,F.,Hattori,S., and Ogawa,H., Original, Research paper (scientific journal), Capital Author

  • Novel carbohydrate-binding activity of bovine liver β-glucuronidase toward lactose/N-acetyllactosamine sequences.

    Glycobiology, 2006.06, Matsushita-Oikawa,H.,Iida-Tanaka,N.,Komatsu,M.,Kanamori,T.,Matsumoto,I.,Seno,N.,and Ogawa,H., Original, Research paper (scientific journal), Capital Author

  • Identification of disialic acid-containing glycoproteins inmouse serum.A novel modification of the light chain of immunoglobulins, vitronectin, and plasminogen

    Glycobiology, 2006.04, Zenta Yasukawa, Chihiro Sato, Kotone Sano, Haruko Ogawa and Ken Kitajima, Original, Research paper (scientific journal), Coauthor

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Published Article 【 display / non-display

  • Dreams of Godmother

    Trends in Glycoscience and Glycotechnology, 2007, 小川温子

  • My research history for 10-years before and after receiving Naito grant for

    Naito Foundation Annual Repport, 2007, 小川温子, Other article

  • 文部省学術調査官時代の思い出とこれからの科研費にかける期待

    Japanese Scienctific Monthly, 2007, 小川温子, Other article

  • 法人化後の研究室と社会

    Functional Glycomics News Letter, 2006, 小川温子

  • 「男女共同参画のために」研究と子育ての両立:現状と問題点、改革への手がかり

    蛋白質核酸酵素, 2005, 日本生化学会ラウンドテーブルディスカッション実行委員会, Coauthor, Introduction and explanation (scientific journal)

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Review Papers 【 display / non-display

  • "The action mechanism of the pseudoproteoglycan probes which inhibit the HIV-1 infection"

    2008.04, Haruko Ogawa, Ken-ichi Tanamoto, Hiroshi, Ushijima, Nana Kawasaki, Public Grants-in-Aid for Scientific Research Report, Joint Work

  • 「生化学」 書評「糖鎖生物学入門」

    日本生化学会, 2006.02, 小川 温子, Other, Individual

  • 特定領域研究報告「グライコミクス」

    2006.01, 小川温子, Public Grants-in-Aid for Scientific Research Report, Joint Work

  • 生理活性糖鎖の構造的基盤と高次生命機能の制御 科研費基盤研究C(1)研究報告書(2004年度)

    人工複合糖質プローブの開発と応用, 2005.03, 小川温子, 木曽 真, Public Grants-in-Aid for Scientific Research Report

  • お茶の水ブックレットNo.4

    糖鎖を操作して健康を守る, お茶の水学術事業会, 2004.09, 小川温子

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Industrial Property 【 display / non-display

  • Preparation method of human pancreatic lipase

    Haruko Ogawa, Kyoko Aikawa, Chihiro Tomita,. Rina Naradate, Tomoko Higami, President of Ochanomizu University