MONAI Hiromu


Position

Assistant Professor

Birth

1984/06

Affiliation

Faculty of Core Research Natural Sciences Division

Organization for Human Life Innovation and Development Institute for Human Life Science

Faculty

Biology

Education Organization (Master's Program)

Biological Sciences

Education Organization (Doctoral Program)

Biological Sciences

URL

写真a

Research Keywords 【 display / non-display

  • brain, neuron, glia

Academic 【 display / non-display

  • Tokyo University of Pharmacy and Life Scineces, School of Life Sciences, University, 卒業, Japan

  • Tokyo Institute of Technology, Interdisciplinary Graduate School of Science and Engineering, Department of Computational Intelligence and Systems Science, Graduate School(Master's Course), 修了, Japan

  • Tokyo Institute of Technology, Interdisciplinary Graduate School of Science and Engineering, Department of Computational Intelligence and Systems Science, Graduate School(Doctor's Course), 修了, Japan

Degree 【 display / non-display

  • 学士(生命科学), 東京薬科大学

  • 修士(理学), 東京工業大学

  • Ph.D, Tokyo Institute of Technology

Campus Career 【 display / non-display

  • Faculty of Core Research Natural Sciences Division, Assistant Professor, 2018.03 -

  • Organization for Human Life Innovation and Development Institute for Human Life Science, Assistant Professor, 2018.03 -

  • Faculty of Science Biology, Assistant Professor, 2018.03 -

  • Headquarters for Research and Innovation, Research Advancement Division, Education and Research Department Center for integrates the humanities and sciences, AI and Data Science, Assistant Professor, 2021.04 -

External Career 【 display / non-display

  • Japan Society for the Promotion of Science, Research Fellowship for Young Scientists DC1, 2010.04 - 2013.03

  • RIKEN Brain Science Institute, Research Fellow, 2013.04 - 2018.02

  • RIKEN Center for brain science, Visiting researcher, 2018.04 -

Research Field 【 display / non-display

 

Books 【 display / non-display

  • 脳を司る「脳」

    講談社ブルーバックス2020.12, 毛内 拡, General book, introductory book for general audience

  • 「気の持ちよう」の脳科学

    筑摩書房2022.11, 毛内 拡, General book, introductory book for general audience

  • 今と未来がわかる 脳と心

    ナツメ社2022.10, 毛内 拡, General book, introductory book for general audience

  • すべては脳で実現している。

    総合法令出版2022.09, 毛内 拡, General book, introductory book for general audience

  • 「アートの理解と塚田の時空間学習則」

    日本神経回路学2022.09, 毛内拡, General book, introductory book for general audience

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Papers 【 display / non-display

  • A Rationally and Computationally Designed Fluorescent Biosensor for d-Serine

    ACS Sens., , vol.6(11)(p.4193 - 4205), 2021.10, Vanessa Vongsouthi, Jason H Whitfield, Petr Unichenko, Joshua A Mitchell, Björn Breithausen, Olga Khersonsky, Leon Kremers, Harald Janovjak, Hiromu Monai, Hajime Hirase, Sarel J Fleishman, Christian Henneberger, Colin J Jackson, Original, Research paper (scientific journal), Coauthor

  • Brain-specific heterozygous loss-of-function of ATP2A2, endoplasmic reticulum Ca2+ pump responsible for Darier’s disease, causes behavioral abnormalities and a hyper-dopaminergic state

    Human Molecular Genetics, , vol.30(18)(p.1762 - 1772), 2021.09, NAKAJIMA Kazuo, ISHIWATA Mizuho, WEITEMIER Adam, SHOJI Hirotaka, MONAI Hiromu, MIYAMOTO Hiroyuki, YAMAKAWA Kazuhiro, MIYAKAWA Tsuyoshi, MCHUGH Thomas, KATO Tadafumi, Original, Research paper (scientific journal), Coauthor

  • Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization

    Scientific Reports, , vol.11(p.8150 - ), 2021.04, MONAI Hiromu, KOKETSU Shinnosuke, SHINOHARA Yoshiaki, UEKI Takatoshi, KUSK Peter, HAUGLAND Natalie,SAMSON Andrew, NEDERGAARD Maiken, HIRASE Hajime, Original, Research paper (scientific journal), Capital Author

  • Transcranial direct current stimulation (tDCS) induces adrenergic receptor-dependent microglial morphological changes in mice,

    ENEURO, , vol.23(p.0204 - 0219), 2019.08, MISHIMA Tsuneko, NAGAI Terumi, YAHAGI Kazuko, AKTHER Sonam, OE Yuki, MONAI Hiromu, KOHSAKA Shinichi, HIRASE Hajime, Original, Research paper (scientific journal), Coauthor

  • Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke

    Proceedings of the National Academy of Sciences, , vol.116(22)(p.11010 - 11019), 2019.05, MONAI Hiromu, WANG Xiaowen, YAHAGI Kazuko, LOU Nanhong, MESTRE Humberto, XU Qiw, ABE Yoichiro, YASUI Masato, IWAI Youichi, NEDERGAARD Maiken, HIRASE Hajime, Original, Research paper (scientific journal), Capital Author

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Published Article 【 display / non-display

  • tDCS metaplasticity and astrocytic calcium in mice

    Brain Stimulation, vol.10(4)(p.e22), 2017.08, H. Hirase, H. Monai, Original, Coauthor, Except for reviews, Research paper, summary (international conference)

  • Transcranial Direct Current Stimulation Alters Microglial Morphology in Mice

    Brain Stimulation, vol.10(4)(p.e24), 2017.08, T. Mishima, Yuki Oe, H. Monai, Hajime Hirase, Original, Coauthor, Except for reviews, Research paper, summary (international conference)

  • P306 Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain

    Clinical Neurophysiology, vol.128(3)(p.e159 - e160), 2017.03, H. Monai, M. Ohkura, M. Tanaka, Y. Oe, A. Konno, H. Hirai, K. Mikoshiba, S. Itohara, J. Nakai, Y. Iwai, and H. Hirase, Original, Capital Author, Except for reviews, Research paper, summary (international conference)

  • 生体脳イメージングのための球面収差補正システムの開発と応用

    光計測シンポジウム2016論文集(p.18 - 20), 2016.10, 上喜裕, 毛内拡, 樋口香織, 西脇大介, 田島鉄也, 岡咲賢哉, 濱裕, 平瀬肇, 宮脇敦史, Original, Coauthor, Except for reviews, Research paper, summary (national, other academic conference)

  • Effects of passive membrane properties of dendrite on dielectric dispersion of neural tissues. -Numerical experiment solving the extended cable equation including the effect of extracellular media.-

    Neuroscience Research, vol.71, 2011.09, H. Monai, T. Ueta, H. Miyakawa, and T. Aonishi, Original, Capital Author, Except for reviews, Research paper, summary (national, other academic conference)

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Review Papers 【 display / non-display

  • 知ってなるほど!脳科学豆知識

    日本脳科学関連学会連合, 2018.08, 電気で脳を活性化!?, Manual etc., Individual

Presentations 【 display / non-display

  • 経頭蓋直流電気刺激が脳の代謝老廃物クリアランスに与える影響の解析

    王 岩・毛内 拡, Domestic, 2023.03, , 日本生理学会, Not Invited, Coauthor

  • Calcium imaging reveals the gut-brain axis via the vagus nerve involvement in the sucrose preference reduction after psychological stress in mice

    山田 芹華・原田 一貴・坪井 貴司・毛内 拡, Domestic, 2023.03, , 日本生理学会, Not Invited, Coauthor

  • Gamma frequency light flicker and auditory tone stimulation induces rapid cortex-wide neroglial Ca2+ elevations

    徐子 涵・毛内 拡, Domestic, 2023.03, , 日本生理学会, Not Invited, Coauthor

  • Effects of Food Viscoelasticity on Memory and Learning in Mice

    田島 実のり・毛内 拡, Domestic, 2023.03, , 日本生理学会, Not Invited, Coauthor

  • アデノ随伴ウイルス発現系を用いた筋萎縮性側索硬化症のモデル開発

    高瀬 未菜・橋本 雅史・大谷 麗子・木村 妙子・毛内 拡・野中 隆・長谷川 成人, Domestic, 2022.11, , 認知症学会, Not Invited, Coauthor

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Prize for Research Activities 【 display / non-display

  • COMMIT2022奨励賞

    毛内拡, 2023.03, Domestic

  • 講談社科学出版賞

    講談社, 毛内拡, 脳を司る「脳」, 2021.09, Domestic

  • 理事長 感謝状

    理化学研究所 , 毛内 拡, 2018.11, Domestic

  • 理事長 感謝状

    理化学研究所 , 毛内 拡, 2018.04, Domestic

  • ベストイメージング賞

    日本バイオイメージング学会, 毛内 拡, BAC-GLT-1-G-CaMP7 #817 系統 (G7NG817)遺伝子改変マウスによる経頭蓋マクロイメージングとその応用, 2017.09, Domestic

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Receipt of outside funds (Education, Research, Contribution to Society and industry-academia[government] collaboration) 【 display / non-display

  • 学術変革領域研究(A)公募研究2022, 3,000Thousand yen

  • 糧食研究会 特定委託研究2022, 2,000Thousand yen

  • 学術変革領域研究(A)公募研究2021, 3,000Thousand yen

  • JST創発的研究支援事業2021, 20,000Thousand yen

  • OLSC(Olympus Life Science Cloud)サービス機能評価2022

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Contributions as an officer, member, etc., of an academic society 【 display / non-display

  • 2019.06 - now,Trustee, Domestic

  • 2017.05 - now,Committee Member, Domestic

Open lectures; lectures, courses, and seminars; guest lectures; etc. 【 display / non-display

  • 睡眠と脳, 第28回睡眠健康指導士上級講座

    2022.10

  • 第3回はこだてブレインサイエンストーク

    2022.08

  • はこだてブレインサイエンストーク in 函館蔦屋書店

    2022.08

  • 「はこだてブレインサイエンストーク in 函館蔦屋書店~ブルーバックス『脳を司る「脳」』出版記念!~」

    2021.02, 函館蔦屋書店

  • ヒューマンライフイノベーションセミナー 腸脳力!~最強の体内物質がヒトを変える~

    2021.01, ヒューマンライフイノベーション研究所

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Media coverage, appearances, commentary, etc. 【 display / non-display

  • TBSラジオ「赤江珠緒たまむすび」の「木曜おもしろい大人」のコーナー

    2022.08.25

  • FM yokohama IMALUの「でぃぐらじ」のコーナー

    2022.08.05

  • 理研、脳卒中で損傷 薬が抑制

    2019.06.03, 日経産業新聞

  • 脳内のK+クリアランス促進が脳卒中後の損傷拡大を抑制する仕組みを解明-理研ら

    2019.05.23, QLife Pro

  • 理研ら,光血栓法で脳損傷を軽減する仕組みを解明

    2019.05.22, OPTRONICS online

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