Research Keywords 【 display / non-display

  • oocyte maturation, apoptosis, meiosis

Research Pursuits 【 display / non-display

  • The number of chromosomes decreases during meiotic division, and it increases upon fertilization. Thus, meiosis and fertilization seem to be biologically independent and different events. However, in many animals, fertilization occurs during meiotic division of oocytes. The timing of fertilization is definitely restricted; fertilization does not occur until meiosis proceeds to an appropriate stage and meiosis reinitiation is induced by fertilization. I am interested in the fact that meiosis and fertilization proceed interactively, and would like to find molecular mechanisms of the interaction using starfish and mouse oocytes.

Educational Pursuits 【 display / non-display

  • Developmental Biology: The molecular mechanisms of fertilization, cleavage, cell division, and organogenesis are covered in this class. Endocrinology: It will be discussed how extracellular signals such as hormones affect whole body and cells. Also, the current important issues will be covered in this class. Laboratory course of developmental biology: Using eggs or oocytes from starfish and frog, meiosis reinitiation, fertilization and cell division are observed. Molecular Developmental Biology: Graduate level lecture and literature discussion in this class covers the molecular mechanisms of development. Other Classes: Scuba Diving course, Science education for science communicator.

Academic 【 display / non-display

  • Tokyo Institute of Technology, Interdisciplinary Graduate School of Science and Engineering, Graduate School(Doctor's Course), Completed, JAPAN

Degree 【 display / non-display

  • Doctor of science

Campus Career 【 display / non-display

  • Graduate School of Humanities and Sciences, Research Organization, the Core Section The Natural/Applied Sciences Division, Professor

  • Faculty of Core Research Natural Science Division, Professor

  • Faculty of Core Research Natural Science Division, Professor

  • Graduate School of Humanities and Sciences, Education Organization, Doctral Program Life Sciences, Professor

  • Graduate School of Humanities and Sciences, Education Organization, Doctral Program Life Sciences, Professor

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External Career 【 display / non-display

  • Tokyo Institute of technology School of science, Research Associate, 1990.04 - 1990.05

  • Tokyo Institute of technology Graduate School of Bioscience and Biotechnology, Research Associate, 1990.06 - 1997.02

  • Ochanomizu University Faculty of Science, Associate Professor (as old post name), 1997.03 - 2005.03

Research Field 【 display / non-display

 

Books 【 display / non-display

  • Caspase-3: Structure, Functions and Interactions

    Activation of Caspase-3/9 in Apoptosis of Starfish Unfertilized Eggs, Nova Sci. Publ., 2020.10, CHIBA Kazuyoshi, Lunawati L Bennett, Research Book, 95-106

  • Report of studies about science literacy

    Competency and literacy, 2014.12, Chiba, Kazuyoshi, Research Book, 23-35

  • サイエンスコミュニケーションー科学を伝える5つの技法

    日本評論社2007.03, 千葉和義・仲矢史雄・真島秀行, Textbook

  • バイオサイエンス

    オーム社2007.05, 室伏きみ子・甲斐広文・熊倉鴻之助・千葉和義・服田昌之, Textbook

  • ライフサイエンス入門

    第二章 ヒトの胚発生と母体環境, オーム社, 2002.12, 千葉 和義, 室伏きみ子, Textbook, 15-24

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Papers 【 display / non-display

  • SGK regulates pH increase and cyclin B-Cdk1 activation to resume meiosis in starfish ovarian oocytes.

    J Cell Biol., vol.218.(p.3612 - 3629), 2019.11, HOSODA Enako, HIRAOKA Daisaku, HIROHASHI Noritaka, OMI Saki, KISHIMOTO Takeo, CHIBA Kazuyoshi, Original, Research paper (scientific journal), Capital Author

  • SGK phosphorylates Cdc25 and Myt1 to trigger cyclin B-Cdk1 activation at the meiotic G2/M transition.

    J Cell Biol., vol.218.(p.3597 - 3611 ), 2019.11, HIRAOKA Daisaku, HOSODA Enako, CHIBA Kazuyoshi, KISHIMOTO Takeo, Original, Research paper (scientific journal), Coauthor

  • POLArIS, a versatile probe for molecular orientation, revealed actin filaments associated with microtubule asters in early embryos.

    Proc. Natl. Acad. Sci. USA, vol.118(11 e2019071118)(p.1 - 12), 2021.01, SUGIZAKI Ayana, SATO Keisuke, CHIBA Kazuyoshi, SAITO Kenta, KAWAGISHI Masahiko, TOMABECHI Yuri , MEHATA Shalin B, ISHII Hirokazu, SAKAI Naoki , SHIROUZU Mikako, TANI Tomomi , TERADA Sumio, Original, Research paper (scientific journal), Coauthor

  • The Starfish Asterina pectinifera: Collection and Maintenance of Adults and Rearing and Metamorphosis of Larvae.

    Methods Mol. Biol., vol.2219(p.49 - 68), 2021, MURABE Naoyuki, OKUMURA Ei-ichi , CHIBA Kazuyoshi, HOSODA Enako , IKEGAMI Susumu , KISHIMOTO Takeo , Original, Research paper (scientific journal), Coauthor

  • Development and evaluation of Ochanomizu University Affiliated Schools “Teaching Materials and Dissertation Database"

    vol.10(p.73 - 78), 2020.03, YAMAGISHI Yuki, MIYAKE Momoko, ARAI Yukio, CHIBA Kazuyoshi, Original, Research paper (scientific journal), Coauthor

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Published Article 【 display / non-display

  • Development of the power of inquiry

    Saitama Kyouiku, 2012, Chiba, K, Single Author, Other article

  • Apoptosis of unfertilized eggs

    Happy School, 2011, Chiba, K, Single Author, Other article

  • プログラムされた卵細胞死

    細胞工学, 2007, 千葉和義, Introduction and explanation (scientific journal)

  • 宇宙人はきっといる!

    楽しい理科授業, 2005, 千葉和義, Introduction and explanation (scientific journal)

Review Papers 【 display / non-display

  • 受精タイミング補正装置として働く減数分裂中期休止機構

    2013.06, 千葉 和義, Public Grants-in-Aid for Scientific Research Report, Individual

  • 文部科学省科学研究費補助金特定領域研究 細胞周期制御 研究成果報告書

    研究項目A02サイクリン依存性キナーゼ, 2007.03, 細胞周期制御研究成果報告書, 岡山博人, Public Grants-in-Aid for Scientific Research Report

  • 受精タイミング補正装置として働く減数分裂中期休止機構

    2007.03, 千葉 和義, Public Grants-in-Aid for Scientific Research Report

  • 受精タイミング補正装置として働く減数分裂中期休止機構

    2006.03, 千葉 和義, Public Grants-in-Aid for Scientific Research Report

  • 細胞内pHとMAPキナーゼによって制御される減数分裂中期休止機構

    2005.03, 千葉 和義, Public Grants-in-Aid for Scientific Research Report

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Presentations 【 display / non-display

  • Decrease of the plasma membrane of starfish oocytes after hormonal stimulation

    YAMAZAKI Yuna, CHIBA Kazuyoshi, Domestic, 2022.03, The Zoological Society of Japan, The Zoological Society of Japan, Not Invited, Coauthor

  • The mechanism of SGK activation in meiosis resumption of starfish oocytes

    LI Mengke, CHIBA Kazuyoshi, Domestic, 2022.03, The Zoological Society of Japan, The Zoological Society of Japan, Not Invited, Coauthor

  • Characterization of ubiquitin-independent proteasomal substrates

    SAKUMA Miho, ENDO Akinori , CHIBA Kazuyoshi , TANAKA Keiji, SAEKI Yasushi, Domestic, 2021.12, The 44nd Annual Meeting of the Molecular Biology Society of Japan, YOKOHAMA, The Molecular Biology Society of Japan, Not Invited, Coauthor

  • Uridylation and decay of maternal mRNA in starfish oocytes

    FURUICHI Megumi, YAMAZAKI Haruka , KAJITANI Reii, ITO Takehiko, CHIBA Kazuyoshi , Domestic, 2021.12, The 43nd Annual Meeting of the Molecular Biology Society of Japan, YOKOHAMA, The Molecular Biology Society of Japan, Not Invited, Coauthor

  • SGK-dependent oocyte maturation in starfish

    CHIBA Kazuyoshi, International, 2021.07, Gametes meet at the time COVID-19., ZOOM, News Gordon Research Conference/ Seminar: Fertilization and Activation of Development, Invited, Main Speaker

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Prize for Research Activities 【 display / non-display

  • 東京都

    Tokyo Metropolitan Government, CHIBA Kazuyoshi, Science education for people living in Tokyo Metropolitan, 2012.10, Domestic

  • (社)日本動物学会奨励賞

    (社)日本動物学会, 千葉 和義, 「ヒトデ卵を用いた減数分裂と受精の研究」, 2004.09, Domestic

  • 第7回 井上研究奨励賞

    千葉 和義, 1991.02, Domestic